EGFR status in oral squamous cell carcinoma: comparing immunohistochemistry, FISH and CISH detection in a case series study

EGFR status in oral squamous cell carcinoma: comparing immunohistochemistry, FISH and CISH detection in a case series study

OBJECTIVES To compare the immunohistochemistry (IHC) expression of epidermal growth factor receptor (EGFR) in oral squamous cell carcinomas (OSCC) with the gene amplification evaluated by fluorescence in situ hybridization (FISH) and chromogenic in situ hybridization (CISH) and their association with clinicopathological parameters. Additionally, we tested the sensibility and specificity of CISH...

Role of EGFR Gene Polymorphisms in Oral Squamous Cell Carcinoma patients of Southeast of Iran: A Case-Control Study

Background: The decisive etiology of Oral squamous cell carcinoma (OSCC)  is still ambiguous, but we recognize the contribution of genetic aberration and environmental agent due to OSCC initiation. In the current study, we elucidate the potential impact of EGFR gene polymorphisms in the risk of OSCC in the southeast of Iran. Methods: Forty-eight OSCC patients along with 100 normal volunteers w...

Correlation of EGFR Expression with Survival Rate in Patients with Oral Squamous Cell Carcinoma

Background and Aim: This study aimed to indicate the role of epidermal growth factor (EGF) in proliferation and growth of epithelial tissue and to determine the correlation be-tween the frequency of expression of EGF receptor (EGFR) by means of immunohistochemistry with survival rate in oral squamous cell carcinoma (OSCC). Materials and Methods: Thirty-eight cases of OSCC diagnosed by hemato...

Short communication: Occurrence of squamous cell carcinoma in a platy fish (Xiphophorus maculatus): A case report

Short communication: Occurrence of squamous cell carcinoma in a platy fish (Xiphophorus maculatus): A case report

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